NIRFlex Solids Transmittance

NIRFlex Solids Transmittance is the latest addition to the range of sampling options for NIRFlex N-500. It is optimized to perform transmission measurements of solid dosage forms, like tablets or capsules, in a very simple and convenient way.

Diffuse transmission measurements are very demanding applications, because only a very small part of the incident light is transmitted. Therefore care must be taken for good signal-to-noise ratio. The design of NIRFlex Solids Transmittance and its optimized detector ensure the best performance. NIRFlex Solids Transmittance uses a low energy source, which avoids any overheating of the samples, therefore enabling the investigation of temperature sensitive pharmaceutical active ingredients (API).

All typical samples like tablets, hard gelatin capsules, powders or soft gelatin capsules including semi-liquids or oily liquids can be measured with the same measurement option: NIRFlex Solids Transmittance. The extremely high dynamic photometric range of the system - one of its outstanding features - allows the generation of spectra with an optimized signal-to-noise ratio for all sample types. In addition, the sample plates are specially designed and coated to prevent stray light caused by light passing around the side of the tablets. All sample plates are customized for optimum measurement conditions for every kind of tablet.

The autosampler accepts up to thirty samples with a diameter of up to 12mm. For samples larger than 12mm, 10-place sample plates are available. The robust design of the measurement cell, with its fixed detector position and the direct drive of the sample plate assure high reproducibility and extremely long lifetime. The legendary robustness of BUCHI NIR spectrometers guarantees seamless calibration transfer from one system to another. As a result, method development can be easily centralized.